myeloma
Biology

myeloma


Term: myeloma
Literally meaning: ?growth of  bone marrow?
Origin: Anc Greek
??????/myelos(=bone marow, core)>???/myo(=be enclosed)
+-???/-oma (suffix denoting state or condition of mass growth)
Coined/History
By Russian phycisian von Rustizky in 1873 for the clinical entity originally described by William McIntyre in 1850 as "mollitis ossium?. During an autopsy, Rustizky found eight separate tumours of the bone marrow, which he designated as ?Multiple Myelomas?. Although Von Rustizky?s did not mention albuminuria (Bence Jones protein), in Russia, the term ?Rustizky?s disease? is often used for multiple myelomaIn 1889  O. Kahler (1849-1893) and H. Huppert (1832-1904) independently introduced the term ?multiple myeloma?.
Definition
Myeloma is a usually malignant tumor of cells that are normally found in the bone marrow like multiple myeloma which arises from abnormal proliferation of plasma cells (responsible for adibodies production).




- Paraprotein
Term: paraproteinLiterally meaning: ?excess of protein?Origin: Anc Greek????-/para-(=pefix denoting intentification, ?beside?, ?near?, ?contrary of? ?side by side? ?past by?, ?beyond?) +????????/proteini(=protein) > ??????/protos(=first or of prime...

- Myelocele
Term: myelocele Literally meaning: rupture of bone marrow OriginAnc Greek??????/myelos(=bone marow, core)>???/myo(=be enclosed)????/kele(=hernia) > ??????/keleos(=burn, rupture)Coined/History(?)Definition Protrusion of spinal cord tissues ...

- Myeloblast
Term: myeloblastLiterally meaning: ?immature or precursor cell of bone marow (or core)?Origin: Anc Greek??????/myelos(=bone marow, core)>???/myo(=be enclosed)+ ??????> blasty (=sprout, germ)  >?????/valo(=push, throw) Coined/HistoryIn 1898,...

- Myelocyte
Term: myelocyteLiterally meaning: ?cell of bone marrow (or core)?Origin: Anc Greek??????/myelos(=bone marow, core)>???/myo(=be enclosed)+cyte (=combining form meaning ?cell? derived from anc Greek word ??????/cytion(=box, container)Coined/History(?)Definition...

- Leukemia
Term: leukemia Origin:  Anc Greek ?????/lephko(=white) + ????/hema(=suffix  pertaining to blood) Coined: by German pathologist Rudolf Virchow (1821?1902), in 1856 who is considered as the father of modern pathology. Virchow was the first to...



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