elastase
Biology

elastase




Term: elastase
Literally meaning: ?separating elastin?
Origin: Anc Greek
????/elao(=be flexibe or ductile)) >??????/elavno(=run, drive)
-???/-asy(=-ase) suffix added to the name of the substrate that the enzyme  hydrolyzes eg proteinase for protein or lipase for lipids
>???-/dia-(=prefix denoting ?through?, ?apart? )
> ???/dio(two) + ??????/stasis(=halt) > ??????/histimi(=stand).

Coined/History
in 1971 an elastolytic enzyme was defined first time which absorbs on elastin from Streptomyces griseus exhibiting specificity toward aminoacids with short aliphatic side chains (Gertler, 1971).   
Sources
1.Gertler A, Hofmann T The involvement of the amino-terminal amino acid in the activity of pancreatic proteases. I. The effects of nitrous acid on elastase, J Biol Chem, 1967.
2. Gertlel A, Trop M The elastase-like enzymes from Streptomyces griseus (pronase).Isolation and partial characterization Eur J Bioch, 1971

Definition
Elastase is a proteolytic enzyme that is produced in pancreas, like trypsin, as an inactive proenzyme , and activated in duodenum by trypsin. 




- Elastin
Term: elastinLiterally meaning: ?protein of flexibility?Origin: Anc Greek????/elao(=be flexibe or ductile)) >??????/elavno(=run, drive)Coined/History  The insolubility of elastin made its isolation difficult until early 1970?s when the soluble...

- Glycosidase
Term: glycosidaseLiterally meaning: ?an enzyme that breaks down glycosides?Origin: Anc Greek??????/glykos(=sweet)+ (-???)/(-asy)(=-ase) enzyme suffix added to the name of the substrate that the enzyme  hydrolyzes eg proteinase for protein or lipase...

- Proteinase K
Term: proteinase (or endopeptidase K) Literally meaning: ?that enzyme which separates proteins?Origin: Anc Greek+????????/proteini(=protein) > ??????/protos(=first or of prime importance) +(-???)/(-asy)(=-ase) enzyme suffix added to the name of the...

- Hydrolase
Term: hydrolaseLiterally meaning: ?enzyme of breaking down water?Origin: Anc Greek????/hydor(=water)+-???/-asy(=-ase) enzyme suffix added to the name of the substrate that the enzyme  hydrolyzes eg proteinase for protein or lipase for lipids >???-/dia-(=prefix...

- Trypsin
Term: trypsinLiterally meaning: ?protein of rubbing?Origin: Greek?????/trivo (=rub, powder, grind) > (simple past) ?????? /etrips? Coined/HistoryThe enzyme named in 1876 by Kuhne who first described an proteolytic activity of pancreatic extract by...



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