Biology
creatine kinase or creatine phosphokinase (CPK)
Term: creatine kinase or creatine phosphokinase (CPK)
Literally meaning: ?enzyme of transfering energy chemical groupto creatine?
Origin: Anc Greek
?????/creas (flesh, meat)
+???/-ine(-ine) = chemical suffix
????/kino(=move)
+(-???)/(-asy)(=-ase) enzyme suffix added to the name of the substrate that the enzyme hydrolyzes eg proteinase for protein or lipase for lipids
>???-/dia-(=prefix denoting ?through?, ?apart? )
> ???/dio(two) + ??????/stasis(=halt) > ??????/histimi(=stand).
Coined/History
Creatine is an organic compound that serves as the energy storage form of cells mainly in muscle fibers. In 1835 French chemist and philosopher Michel-Eugene Chevreul (1786-1889) discovered it in the juice of flesh and named by him. Creatine kinase was first described by Lohmann in 1934 who showed in extracts of skeletal muscle the two labile phosphate groups of ATP were trransfererred to creatine. The reveraibility of the reaction was demonstrated by Lohmann (1935) and Banga in 1943 effected a partial purification of the enzyme .
Sources
1. Lohmann, K. (1934). Biochem. Z. 271, 264
2. Lehmann, H. (1935). Biochem. Z. 281, 271
3. Banga, I.(1943). Stud. Inst. med. Chem. Univ. Szeged, 8, 59
Definition
Creatine kinase (CK) is a kinase that converts creatine to phosphocreatine consuming ATP.
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Lipase
Term: lipaseLiterally meaning: ?the enzyme that breaks down lipids?Origin: Anc Greek+ ?????/?????(=fat, grease) >????? > verb ?????/livo(=grease)+(-???)/(-asy)(=-ase) enzyme suffix added to the name of the substrate that the enzyme hydrolyzes...
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Rabdomyolysis
Term: rabdomyolysis Literally meaning: ?desrtuction of skeletal (striated) muscle? Origin: Anc Greek??????/rabdos(=rod, stripe, stick)+???-/myo-(=combining form meaning muscle) >???/mys/(=muscle) >???/myo(=enclosed like the muscle inside body...
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Phosphocreatine
Term: phosphocreatineLiterally meaning: ?phosporylated creatine?Origin: Anc Greek?????-/phospho(=phospho-, prefix denoting a chemical bound with phosporous group) > ???/phos=light +????????/creatine(=creatine, an organic acid that helps to supply energy...
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Creatinine
Term: creatinine Literally meaning: (feminine)"flesh component"Origin: (Greek)????????/creatine(=creatine, an organic compound that in phosphorylated form (phosphocreatine), serves as the energy storage form of cells mainly in muscle...
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Kinase
Term: kinase Origin: Anc Greek????/kino(=move) +(-???)/-asy(=-ase) enzyme suffix added to the name of the substrate that the enzyme hydrolyzes eg proteinase for protein or lipase for lipids Coined:? Definition: Kinases are enzymes that catalyze...
Biology