rabdomyolysis
Biology

rabdomyolysis



Term: rabdomyolysis

Literally meaning: ?desrtuction of skeletal (striated) muscle?

Origin: Anc Greek
??????/rabdos(=rod, stripe, stick)
+???-/myo-(=combining form meaning muscle) >???/mys/(=muscle) >???/myo(=enclosed like the muscle inside body or rat in its nest=epimys)
+?????/lysis (=dissolution, degradation, decomposition, destruction)  > verb ???/leo =break down, solve, loose, degradate).

Coined/History
  The rhabdomyolysis syndrome was initially observed in the 13th century BCE in the Bible and was presumed to be caused by the human ingestion of migratory quail that consume large amounts of hemlock (conium) seeds. The disease was reported in Germany in 1881, but the first cases of crush syndrome and acute renal failure (ARF) were reported during the Sicilian earthquake in Messinain 1908, and in the German medical literature during World War I.
Sourse: Bywaters EGL, Beall D. Crush injuries with impairment of renal function. BMJ. 1941;1:427.

Definition
Rabdomyolysis is a potentially life-threatening syndrome in which muscle cells break down resulting in release of muscle proteins such as myoglobin and creatine phosphokinase in bloodstream. Patients are characterised by muscle weakness, muscular aches, brown colored urine  and an elevated plasma creatine kinase (CK) level. Rhabdomyolysis is caused by many factors such as medications (eg statins), trauma, toxins, gene mutations or viral infections.  Rhabdomyolysis may be inherited or acquired. 




- Creatine Kinase Or Creatine Phosphokinase (cpk)
Term: creatine kinase or creatine phosphokinase (CPK)Literally meaning: ?enzyme of transfering energy chemical groupto creatine?Origin: Anc Greek?????/creas (flesh, meat)+???/-ine(-ine) = chemical suffix????/kino(=move)+(-???)/(-asy)(=-ase) enzyme suffix...

- Myocardium
Term: myocardiumLiterally meaning: ?muscle he?rt?Origin: Anc Greek??o/myo-(=combining form denoting muscle) >mys/ (=muscle, mouse) > ???/myo(=enclosed, like the muscle inside body or the rat in its nest=epimys)+ ?????? /kardia (=heart) > derived...

- Perimysium
Term: perimysiumLiterally meaning: ?around the muscle?Origin: Anc Greek????-/peri- (=combining form meaning  ?around?)+ ???/mys/ (=muscle, mouse) > ???/myo(=enclosed, like the muscle inside body or the rat in its nest=epimys)+-um=latin suffix...

- Myalgia
Term: myalgiaLiterally meaning: ?pain of the muscle?Origin: Anc Greek+???-/myo-(=combining form meaning muscle) > ???/mys/ (=muscle) > ???/myo(=enclosed like the muscle inside body or rat in its nest=epimys)?????/algos(=ache, pain) > ??????/loigos(=pain,...

- Cardiomyopathy
Term: cardiomyopathy Literally meaning: " affection of heart muscle"Origin: Anc Greek?????? /kardia (=heart) which derived according Meletios(7th-8th cen AD) probably from verb >????????/kradeno (=rattle, rock) ???/mys/ (=muscle) > ???/myo(=enclosed...



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