plasmin
Biology

plasmin



Term: plasmin
Literally meaning: ?plasma protein?
Origin: Anc Greek
??????(noun)/plasma (=something formed or molded, an idol) > ??????/plasso(=create, form, mold)
Coined/History
In 1933 Tillett and Garner discovered a fibrinolytic component contained within a broth culture of haemolytic Streptococci. In 1949 Tillett with Sol Sherry named this component streptokinase (SK) and administered this to patients for treatment of fibrinous adhesions.  By 1957 the active form of this enzyme was called plasmin and its inactive form plasminogen.
Sources
1.          Tillet WS, Garner RL. The fibrinolytic activity of hemolytic streptococci. J Exp Med 1933; 58:485-502.
2.         Tillett WS, Sherry S. The effect in patients of streptococcal fibrinolysin (streptokinase) and streptococcal deoxyribunuclease on fibrinous, purulent and sanguineous pleural exudations. J Clin Invest 1949; 28:173-90.
3.         3. Cliffton EE. The use of plasmin in humans. Ann NY Acad Sci 1957; 68: 209-29.

Definition
Plasmin is a proteolytic enzyme for blood plasma proteins especialy for fibrin clots, after its activation of its proenzyme form, the plasminogen. Human plasmin is encoded by PLG gene and gene mutations may cause thrombosis.  




- Plasmapheresis
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- Plasmacyte
Term: plasmacyteLiterally meaning: ?plasma cell?Origin: Anc Greek?????? (noun)/plasma (=something formed or molded, an idol)> ??????/plasso(=create, form, mold).+????-/cyto- (=combining form meaning ?cell? derived from anc Greek ??????/kytion/cytion=box,...

- Apoplast
Term:apoplastOrigin: Anc Greek???-/apo(=away from)?????? (noun)/plasma(=something formed or molded, an idol) > ??????/plasso(=create, form, mold) literally apoplast means that thee is a distinction or detachment  of cell protoplast in a plant...

- Plasmid
Term: plasmidOrigin: Anc Greek ?????? (noun)/plasma(=something formed or molded, an idol) > ??????/plasso(=create, form, mold) -????/idio(=-id, suffix that is used as diminutive of a noun )original meaning of plasma: substance of uncertain shape.Joshua...

- Coagulation Factors And Related Substances
Number and/or name Function Associated genetic disorders I (Fibrinogen) Forms clot (fibrin) Congenital afibrinogenemia, Familial renal amyloidosis II (Prothrombin) Its active form (IIa) activates I, V, VII, VIII, XI, XIII,...



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