Biology
- Expressed Gene Number Can Be Measured En Masse
KEY CONCEPTS:"Chip" technology allows a snapshot to be taken of the expression of the entire genome in a yeast cell. ~75% (~4500 genes) of the yeast genome is expressed under normal growth conditions. Chip technology allows detailed comparisons of related...
- Genes Are Expressed At Widely Differing Levels
KEY TERMS:The abundance of an mRNA is the average number of molecules per cell. Abundant mRNAs consist of a small number of individual species, each present in a large number of copies per cell. Scarce mRNA (Complex mRNA) consists of a large number...
- Homework
Food chains and webs questions (the previous homework) Finish the analysis questions. Please make sure that all your answers are clear, detailed and answer the question. Make sure that you look up any spellings that you are unsure of. Your homework...
- Unifying Themes In Biology
this will be built on heavily as posting progresses. These unifying ideas should help to make it so that the interconnectivity of biology is clearer, so while learning, questions like "what is this all for/why is it important?" can be answered. 1. Emergent...
- Metabonomics, Metabolonomics
Term: metabonomics, metabolonomics Origin: Anc Greek ????????/metaboli(=change)?????/nomos(=law)-omics is a suffix which originally was used in word ?genomics> genome =gene + chromosome in order to indicate the complete set of chromosomes and the genes...
Biology
meta-analysis
Term: meta-nalysis
Literally meaning: ?breaking up or study after?
Origin: Anc Greek
????-/meta-(=compining form meaning after, next to, behind)
????????/analysis(=to breaking up of any whole into its parts)>verb ??????/analeo >???- /ana-(= combining form meaning upon, throughout) + ???/leo(to break up, to solve)
Coined/History
The first meta-analysis was performed in 1904 by Karl Pearson when he was asked by the British government to review evidence on the effects of a vaccine against typhoid. The term was coined in 1976 by American statistician Gene Glass in his presidential address to the American Educational Research Association (AERA) : ? ? the analysis of the results of statistical analysis for the purpose of drawing general conclusions?. One of the first meta-analysis published was on the effect of class size on educational achievement (Glass and Smith, 1979).
Source:
Simpson, R; Pearson, K (1904). "Report On Certain Enteric Fever Inoculation Statistics". The British Medical Journal(BMJ Publishing Group) 2 (2288): 1243?1246. JSTOR 20282622. PMC 2355479. PMID 20761760.
Glass G. V (1976). "Primary, secondary, and meta-analysis of research". Educational Researcher 5: 3?8.
Definition
????-analysis is the statistical methods of combining evidence from different studies in order to obtain a quantitative estimate of the overall effect of a particular innervation or treatment. In other words meta-analysis is the systematic approach for integrating the outcomes of a set of studies.
- Expressed Gene Number Can Be Measured En Masse
KEY CONCEPTS:"Chip" technology allows a snapshot to be taken of the expression of the entire genome in a yeast cell. ~75% (~4500 genes) of the yeast genome is expressed under normal growth conditions. Chip technology allows detailed comparisons of related...
- Genes Are Expressed At Widely Differing Levels
KEY TERMS:The abundance of an mRNA is the average number of molecules per cell. Abundant mRNAs consist of a small number of individual species, each present in a large number of copies per cell. Scarce mRNA (Complex mRNA) consists of a large number...
- Homework
Food chains and webs questions (the previous homework) Finish the analysis questions. Please make sure that all your answers are clear, detailed and answer the question. Make sure that you look up any spellings that you are unsure of. Your homework...
- Unifying Themes In Biology
this will be built on heavily as posting progresses. These unifying ideas should help to make it so that the interconnectivity of biology is clearer, so while learning, questions like "what is this all for/why is it important?" can be answered. 1. Emergent...
- Metabonomics, Metabolonomics
Term: metabonomics, metabolonomics Origin: Anc Greek ????????/metaboli(=change)?????/nomos(=law)-omics is a suffix which originally was used in word ?genomics> genome =gene + chromosome in order to indicate the complete set of chromosomes and the genes...