hypochondroplasia
Biology

hypochondroplasia



Term: hypochodroplasia
Literally meaning: ?diminished cartilage formation?
Origin: Anc Greek
???-/hypo- (prefix meaning "under", "beneath", "less", ?diminished?)
+???????/chondros (=thick, coarse salt,  soft bone, carilages in the region between the ribs and navel)
+??????/plasso(=to create, to form, to mold)
Coined/History
  Dwarfism was known since times of ancient Egypt as Egyptians had  two dwarf gods: Bes, the protector of sexuality/childbirth  and Ptah the protector of regeneration.
Hypochondroplasia was probably first described by Ravenna (1913) but not generally recognized until much later, the term being coined by Maroteaux and Lamy (1960).
Sources
Ravenna F (1913) Achondroplasie et chondrohypoplasie: contribution clinique. N Iconogr Salpetriere 26:157?184.
Maroteaux P, Lamy M (1960) Les chondropdystrophies genotypiques. L?Expansion Scientifique Francaise, Paris, pp 26?27.

Definition
Hypochondroplasia (MIM 146000) is is an autosomal dominant skeletal dysplasia characterized by short extremities, short stature and lumbar lordosis, usually exhibiting a phenotype similar to but milder than achondroplasia. Hypochodroplasia may be inherited as an autosomal dominant trait due to mutations in FGFR3 gene, although most cases occurs as spontaneous mutations in germline.   




- Hypoplasia
Term: hypoplasiaLiterally meaning: ?underdevelopment?Origin: Anc Greek???-/hypo- (prefix meaning "under", "beneath", "less", ?diminished?)+??????/plasis(=formation) ??????/plasso(=to create, to form, to mold) Coined/History(?)DefinitionHypoplasia is...

- Osteochondroma
Term: osteochondromaLiterally meaning: ?growth of bones and cartllage?Origin: Anc Greek'ï???[õ?/ostoun(=bone)+???????/chondros (=thick, coarse salt,  soft bone, cartilages in the region between the ribs and navel)+(-???)/(-oma)=suffix...

- Achondroplasia
Term: achodroplasiaLiterally meaning: ?without cartilage formation?Origin: Anc Greek?-/a (privative, ?non?)+???????/chondros (=thick, coarse salt,  soft bone, cartilages in the region between the ribs and navel)+??????/plasso(=to create, to form,...

- Hypochondria Etymology
Term: hypochondriaLiterally meaning: ?under the cartilage of the breastbone?Origin: Anc Greek???/hypo (prefix meaning "under", "beneath", "less")+ ???????/chondros (=thick, coarse salt,  soft bone, carilages in the region between the ribs and navel)...

- Hypochondria
Term: hypochondriaLiterally meaning: ?under the cartilage of the breastbone?Origin: Anc Greek???/hypo (prefix meaning "under", "beneath", "less")+ ???????/chondros (=thick, coarse salt,  soft bone, carilages in the region between the ribs and navel)...



Biology








.