hapten
Biology

hapten


Term: hapten (parial or incomplete antigen)

???? Origin: Anc Greek
????/hapto (=fasten, adapt, clasp, bind or grasp)

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Karl Landsteiner
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? ???Coined: in 1921 by the American biologist of Austrian origin, Karl Landsteiner (1868 ? June 26, 1943). In 1930, Landsteiner received the Nobel Prize for Medicine for his work on differentiating the blood groups

Definition:
A hapten is a small molecule that can stimulate an strong immune response only when it is in combination with a larger molecule such as a protein. Functionally , a hapten is virtually the equivalent of en epitope.




- # 60 Action Of B-lymphocytes
A B-lymphocyte places some of its specific receptor molecules in its cell surface membrane. If it encounters an antigen that binds with this receptor, the B-lymphocyte is activated. It divides repeatedly by mitosis to produce a clone of genetically identical plasma...

- Antigen
Term: antigen Literally meaning: ? antibody generator?Origin: Anc Greek????-/anti- (=prefix meaning opposed to, against, instead) + ?????/geno(=produce, give birth to)Coined/HistoryBy Hungarian physician and microbiologist Laszlo Detre (1874-1939)...

- Polymorphism
Term: polymorphismLiterally meaning: ?having multiple forms"Origin: Anc Greek????-/poly-(=many, several)+ ?????/morphe(=shape, form) Coined/HistoryThe first polymorphism was recorded in 1900 by Landsteiner and it was the ABO blood group polymorphisms.Definition(genetics)...

- Plasma
Term: plasmaOrigin: Anc Greek ?????? (noun)/plasma(=something formed or molded, an idol) > ??????/plasso(=create, form, mold) original meaning: a substance without shape Coined: ?The term "plasma membrane" was coined by a Swiss botanist Karl Wilhelm...

- Epitope
Term: epitope Origin: Anc Greek ???-/epi(=prefix meaning upon, on)?????/topos(=place, location) Niels Kaj Jerne (1911-1994)Coined: in 1960 by Danish immunologist Niels Kaj Jerne (1911?1994) who proposed that an antigen particle carries several epitopes....



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