myosin
Biology

myosin



Term: myosin
Literally meaning: ?pertaining to muscle?
Origin: Anc Greek
???-/myo-(=combining form meaning muscle) > ???/mys/ (=muscle) > ???/myo(=enclosed like the muscle inside body or rat in its nest=epimys)
Coined/History 
The term was coined in 1864 by W. Kuhne who called ?myosin? a viscous protein that he had extracted from muscle with concentrated salt solution. Many years later (1939) V. A. Engelhardt and M.N. Lyubimova reported that myosin had ATPase activity. In years 1942 and 1943 A. Szent-Gyogyi and F.B. Straub proved that another protein which was named (by Straub)  ?actin? when compined with myosin was responsible for muscle viscosity and contractility.
 Sources
Kühne, W. 1864. Untersuchungen über das Protoplasma und die Contractilitat. W. Engelmann, Leipzig.
Engelhardt, V.A., and M.N. Lyubimova. 1939. Myosin and adenosinetriphosphatase.Nature. 144:668?669.
Straub, F.B. 1942. Actin. Stud. Inst. Med. Chem. Univ. Szeged. II:3?15.
Szent-Györgyi, A. 1943a. The crystallization of myosin and some of its properties and reactions. Stud. Inst. Med. Chem. Univ. Szeged. III:76?85.
Definition
Myosin is any of motor protein from a large family which are involved in motility processes such as muscle  contraction through ATP hydrolysis. Myosins are interact with other motor proteins like actin-filaments. Sarcomeric myosin is a large hexameric protein with two globular heads (conatining binding sites for actin thin filaments and ATP)  and a long coiled-coil a-helical rod. 




- Mrna Can Be Specifically Localized
KEY CONCEPTS:Yeast Ash1 mRNA forms a ribonucleoprotein that binds to a myosin motor. A motor transports it along actin filaments into the daughter bud. It is anchored and translated in the bud, so that the protein is found only in the bud. An mRNA is...

- Actin
In this picture you can see the muscle contraction present when someone flexes his or her arm. Actin is the most abundant protein in Eukaryotes and it has many functions. Actin participates in many important cellular processes like muscle contraction,...

- Tropomyosin
Term: tropomyosin Literally meaning: ?that which is turned in muscle?Origin: Anc Greek+-??????/tropos(=suffix denoting way, habit, direction or tendency) >?????/trepo(=turn)+???-/myo-(=combining form meaning muscle) > ???/mys/ (=muscle) > ???/myo(=enclosed...

- Sarcomere
Term: sarcomere Literally meaning: ?part of flesh? Origin: Anc Greek????/sarx(=flesh) >genitive form ??????/sarcos+?????/meros(=part) Coined/History(?)DefinitionSarcomere is the basic functional contractile units  of a muscle which is composed...

- Paramyosin
Term: paramyosinLiterally meaning: ?beside/like myosin?Origin: Anc Greek????-/para-(=pefix denoting intentification, ?beside?, ?near?, ?contrary of? ?side by side? ?past by?, ?beyond?) +???-/myo-(=combining form meaning muscle) > ???/mys/ (=muscle)...



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