kinetochore
Biology

kinetochore


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Term: kinetochore
Origin: Anc Greek
???????/kinisis/(=movement) >
?????/choros (=place, region)
Coined:
The term introduced in 1934 by L.W. Sharp in his well-known text book (cf.chapter F, Introduction to Cytology) two years earlier than centromere was recommended by Cyril Dean  Darlington  (1936)
Definition:
Kinetochore is the precise region that joins the two identical sister chromatids of  a chromosome within centromere.

Comment
Centromere and kinetochore where considered synonyms until 1981. In 1981 Ris and Witt defined the term ?kinetochore?  as the precise region on the chromososme that becomes attached to spindle and it is visible only in ultra-thin electron microscope sections. Centromere is the chromosomal region with which the kinetochore is associated (Rieder 1982).
Sourse
Emilio Battaglia. Centrmere, kinetochore, kinochore, kinetosome, kinosome, kinetomere, kinomere, kinetocentre, kinocentre: history, etymology and interpretation. Caryologia, Vol 56, no 1:1-21, 2003.






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