Biology

dystrophin

Term: dystrophin

Literally meaning: ?malnutrition ?

Origin: Anc Greek

+???-/dys-(=prefix used with a negative sense meaning ?difficult?, ?bad?, ?abnormal?, ?misfortune?) > ???/dyo(=decline) ????/dysi(=sundown)

+ ?????/trophe(=food, nourishment )> ?????/drepo(=gather))

Coined/History

In the 1860s French physician Guillaume Duchenne (1806-1875) noticed that the muscles in some young boys were weakening as he believed that dystrophy progressed as muscles continued to develop without the nutrients they needed. In 1987 a protein was identified that named dystrophin because of its abnormal form causes muscular dystrophy.

Sourse

Hoffman E, Brown R, Kunkel L (1987). "Dystrophin: the protein product of the Duchenne muscular dystrophy locus". Cell 51 (6): 919?28.

Definition

Dystrophin is a large (427kDa) muscle cytoskeleton protein, 3684 aminoacids long, with significant role in the maintance of cellular structure. In humans, the absence or abnormality of dystrophin leads to Duchenne or Becker muscular dystropy.

- Angiodystrophy
Term: angiodystrophyLiterally meaning: ?delay of growth due to vessel?Origin: Anc Greek??????/aggio (=vessel, receptacle) > ?????/aggos(=tube)+???-/dys-(=prefix used with a negative sense meaning difficult, bad, abnormal, misfortune) > ???/dyo(=decline)...

- Pseydohypertrophy
Term: pseydohypertrophyLiterally meaning: ?untrue overgrowth?Origin: Anc Greek??????/pseydos(=????-/hyper(=combining form denoting ?over?)+ ?????/trophe(=food, nourishment )> ?????/drepo(=gather)) Coined/HistoryIn 1868 by Duchenne de Boulogne (1806...

- Lipodystrophy
Term: lipodystrophyLiterally meaning: delay of the growth of adipose tissueOrigin: Anc Greek?????/?????(=fat, grease) >????? > verb ?????/livo(=grease)+???-/dys-(=prefix used with a negative sense meaning difficult, bad, abnormal, misfortune) >...

- Leucodystrophy
Term: leucodystrophyLiterally meaning:. Delay of the growth of the white matterOrigin: Anc Greek ??????/leucos(=white)+???-/dys-(=prefix used with a negative sense meaning difficult, bad, abnormal, misfortune) > ???/dyo(=decline) ????/dysi(=sundown)+...

- Dys-
dys-Origin: Anc Greek???-/dys-(=prefix used with a negative sense meaning difficult, bad, abnormal, misfortune) > ???/dyo(=decline) ????/dysi(=sundown) dystrophy, dysfunction, dysarthria, dysgenesis, dyspnea, dysphagia, dysplasia, dystonia...

Biology