desmin
Biology

desmin



Term: desmin
Literally meaning: ?binding protein?
Origin: Anc Greek
???/theo(=to bind) > ??????/desmos(=bond)
Coined/History 
Desmin is a protein of vertebrates first described in 1976, and purified in 1977
Definition
Desmin is a 52kD protein that is subunit of intermediate filament found near the Z line in sarcomere of muscle. It is encoded by DES gene mutations of which cause myopathy myofibrillar type 1 (MFM1) or desmin-related myopathy (DRM) .




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