Comparison between Spontaneous and Induced mutations
Biology

Comparison between Spontaneous and Induced mutations



Spontaneous and Induced mutations: 
Major differences


Spontaneous mutations
Induced mutations
1.      It is caused by natural agents, so it is also known as natural mutations or background mutations.
It is caused by man
2.      Frequency of mutation is very low (about one per million genes)
It is very faster
3.      It is due to  mutagens in many cellular products such as formaldehyde, nitrous acid, peroxides etc
It is due to physical mutagens (radiations, temperature etc) and chemical mutagens (mustard gas, vinyl chloride, acridine dyes, ammonia etc)





- Genomes Can Be Mapped By Linkage, Restriction Cleavage, Or Dna Sequence
Defining the contents of a genome essentially means making a map. We can think about mapping genes and genomes at several levels of resolution:A genetic (or linkage) map identifies the distance between mutations in terms of recombination frequencies....

- An Interrupted Gene Consists Of Exons And Introns
KEY CONCEPTS:Introns are removed by the process of RNA splicing, which occurs only in cis on an individual RNA molecule. Only mutations in exons can affect protein sequence, but mutations in introns can affect processing of the RNA and therefore prevent...

- Mutations Are Concentrated At Hotspots
KEY TERMS:A hotspot is a site in the genome at which the frequency of mutation (or recombination) is very much increased, usually by at least an order of magnitude relative to neighboring sites. KEY CONCEPTS: The frequency of mutation at any particular...

- Mutations May Affect Single Base Pairs Or Longer Sequences
KEY TERMS:A point mutation is a change in the sequence of DNA involving a single base pair. A transition is a mutation in which one pyrimidine is replaced by the other and/or in which one purine is replaced by the other. A transversion is a mutation...

- Progeria
Gene Regulation and Mutation:  Vocabulary:-gene regulation: ability of an organism to control which genes are transcribed in response to the environment -operon: section of DNA thatcontains the genes for the proteins needed for a specificmetabolic pathway-mutation:...



Biology








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