Biology
#14. Globular and fibrous proteins - haemoglobin and collagen
Globular and
Fibrous are 2 main types of proteins with a 3D structure.
1. Haemoglobin, a globular protein
- Composed of 2 ? + 2 ? polypeptide chains + 1 inorganic prosthetic haem group.
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Hb's function: carry O2 from lungs to respiring tissues. |
2. Collagen - a fibrous protein- Composed of 3 polypeptide chains wound around each other. Each chain is a coil itself of around 1000 amino acids.
- Structure strength is increased by forming:
- H bonds between the 3 polypeptide chains.
- Collagen molecules wrapped around each other ---> Collagen Fibrils
- Collagen Fibrils ---> Collagen Fibres.
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Collagen's function: support and elasticity in many animal tissues (human skin, bone and tendons). |
3. Test for proteinsThe Biuret Test shows the presence of
peptide bonds, which are the basis for the formation of proteins. These bonds will make the
blue Biuret reagent turn
purple.
Add biuret solution. A purple colour indicates the presence of protein.
Syllabus 2015
(h) describe the molecular structure of haemoglobin as an example of a globular protein, and of collagen as an example of a fibrous protein and relate these structures to their functions (the importance of iron in the haemoglobin molecule should be emphasised. A haemoglobin molecule is composed of 2 alpha (?) chains and 2 beta (?) chains, although when describing the chains the terms ?-globin and ?-globin may be used. There should be a distinction between collagen molecules and collagen fibres);
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Syllabus 2016 c) describe the molecular structure of haemoglobin as an example of a globular protein, and of collagen as an example of a fibrous protein and relate these structures to their functions (The importance of iron in the haemoglobin molecule should be emphasised. A haemoglobin molecule is composed of two alpha (?) chains and two beta (?) chains, although when describing the chains the terms ?-globin and ?-globin may be used. There should be a distinction between collagen molecules and collagen fibres) |
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Biology