Biology
- Gene Mutation
A gene mutation is a change in one or several bases. A base may be added, deleted, or substituted with another base. This is caused often through the action of damaging chemicals, radiations, or through errors inherent in DNA replication and repair reactions....
- #37 Summary Of Genetic Control
1. DNA and RNA are polynucleotides, made up of long chains of nucleotides. 2. A nucleotide contains a pentose sugar, a phosphate group and a nitrogen-containing base. In RNA the sugar is ribose, and in DNA it is deoxyribose. 3. A DNA molecule consists...
- # 36 Gene Mutation, Sickle Cell Anaemia
A gene mutation is a change in the sequence of nucleotides that may result in an altered polypeptide. A mutation is a random, unpredictable change in the DNA in a cell. It may be: ? a change in the sequence of bases in one part of a DNA molecule?...
- # 35 The Genetic Code - Protein Synthesis
The genetic code specifies the amino acids that are assembled to make polypeptides. The way that DNA codes for polypeptides is central to our understanding of how cells and organisms function. A polypeptide is coded for...
- # 34 Dna Structurer And Replication
DNA molecule consists of nucleotides in which the sugar component is deoxyribose whereas the RNA molecule has nucleotides in which the sugar is a ribose. Nucleotides Roles: are monomers for nucleic acid polymers, such as DNA and RNA....
Biology
# 33.1 Nucleic acids and protein synthesis - Syllabus 2015
? Structure and replication of DNA
? Role of DNA in protein synthesis
Learning Outcomes
Candidates should be able to:
(a) describe the structure of RNA and DNA and explain the importance of base pairing and the different hydrogen bonding between bases (includes reference to adenine and guanine as purines and to cytosine, thymine and uracil as pyrimidines. Structural formulae for bases is not required but the
recognition that purines have a double ring structure and pyrimidines have a single ring structure should be included);
(b) explain how DNA replicates semi-conservatively during interphase;
(c) state that a polypeptide is coded for by a gene and that a gene is a sequence of nucleotides that forms part of a DNA molecue and state that a mutation is a change in the sequence that may result in an altered polypeptide;
(d) describe the way in which the nucleotide sequence codes for the amino acid sequence in a polypeptide with reference to the nucleotide sequence for HbA (normal) and HbS (sickle cell) alleles of the gene for the ?-globin polypeptide;
(e) describe how the information on DNA is used during transcription and translation to construct
polypeptides, including the role of messenger RNA (mRNA), transfer RNA (tRNA) and the ribosomes (for genetic dictionaries see section 5);
(f) use the knowledge gained in this section in new situations or to solve related problems.
? Role of DNA in protein synthesis
Learning Outcomes
Candidates should be able to:
(a) describe the structure of RNA and DNA and explain the importance of base pairing and the different hydrogen bonding between bases (includes reference to adenine and guanine as purines and to cytosine, thymine and uracil as pyrimidines. Structural formulae for bases is not required but the
recognition that purines have a double ring structure and pyrimidines have a single ring structure should be included);
(b) explain how DNA replicates semi-conservatively during interphase;
(c) state that a polypeptide is coded for by a gene and that a gene is a sequence of nucleotides that forms part of a DNA molecue and state that a mutation is a change in the sequence that may result in an altered polypeptide;
(d) describe the way in which the nucleotide sequence codes for the amino acid sequence in a polypeptide with reference to the nucleotide sequence for HbA (normal) and HbS (sickle cell) alleles of the gene for the ?-globin polypeptide;
(e) describe how the information on DNA is used during transcription and translation to construct
polypeptides, including the role of messenger RNA (mRNA), transfer RNA (tRNA) and the ribosomes (for genetic dictionaries see section 5);
(f) use the knowledge gained in this section in new situations or to solve related problems.
- Gene Mutation
A gene mutation is a change in one or several bases. A base may be added, deleted, or substituted with another base. This is caused often through the action of damaging chemicals, radiations, or through errors inherent in DNA replication and repair reactions....
- #37 Summary Of Genetic Control
1. DNA and RNA are polynucleotides, made up of long chains of nucleotides. 2. A nucleotide contains a pentose sugar, a phosphate group and a nitrogen-containing base. In RNA the sugar is ribose, and in DNA it is deoxyribose. 3. A DNA molecule consists...
- # 36 Gene Mutation, Sickle Cell Anaemia
A gene mutation is a change in the sequence of nucleotides that may result in an altered polypeptide. A mutation is a random, unpredictable change in the DNA in a cell. It may be: ? a change in the sequence of bases in one part of a DNA molecule?...
- # 35 The Genetic Code - Protein Synthesis
The genetic code specifies the amino acids that are assembled to make polypeptides. The way that DNA codes for polypeptides is central to our understanding of how cells and organisms function. A polypeptide is coded for...
- # 34 Dna Structurer And Replication
DNA molecule consists of nucleotides in which the sugar component is deoxyribose whereas the RNA molecule has nucleotides in which the sugar is a ribose. Nucleotides Roles: are monomers for nucleic acid polymers, such as DNA and RNA....